Head of Computational Biology

As a Head of Computational Biology at NextRNA Therapeutics, you will join an interdisciplinary team of highly creative and talented individuals whose mission is to bring a new class of small molecule medicines to patient in need. You will have a key role in identifying, validating and drug novel long non-coding RNA targets. You will be a key team member responsible for utilizing NextMAP™, NextRNA’s proprietary computation engine that identifies driving disease lncRNAs. In collaboration with the biology and drug discovery team, you will provide translation guidance for the mechanism of action and patient stratification for the lead programs. As a member of the leadership team, you will have the opportunity to contribute to the development of the company’s overall strategy.

About you:

• You are a real team player and leader whose collaboration is one of your best strengths.
• You are conscientious, organized, and detailed oriented.
• You are curious, love learning and are eager to do what it takes to solve hard problems.
• You thrive in a fast-paced environment and enjoy pushing the edge of what is possible.
• You enjoy wearing several hats and volunteer to take additional responsibilities for the good of the company and the team.
• You advocate for best practices/collaboration in code development.

What you’ll do:

• Develop and lead CompBio strategy, participate and present if needed to Science Board meeting and contribute to partnerships diligence.
• Manage team members to ensure coordination and alignment of roles and responsibilities within projects.
• Coordinate and Review the CompBio team’s data-driven deliverables that contribute to stage-gate decision for portfolio programs.
• Manage/oversee pipeline development focused on multi-omics, isoform detection/discovery, and SHAPEMaP with data from patient and cell lines.
• Initiate and lead cross-functional translational science strategic initiatives.
• Coordinate interfaces across Research & Development Oncology/Neurology, Data Management/Science, and IT functions.

Key Qualifications:

• PhD degree in computational biology, bioinformatics, data science, or a related field.
• 15 years post PhD experience with minimum 10 years of industry including 5 years in managerial position.
• Previous experience in managing and leading computational biology teams to support drug discovery stage from target discovery to IND filling is required
• Knowledge on RNA biology is required (gene regulation at isoform level)
• Experience in working on oncology and/or neuroscience is a plus
• Demonstrated critical thinking skills and learning agility, highly self-motivated, with an aspiration of continuous improvement of oneself and others
• Effective influencer, communicator, and team player with proven networking skills, both internally and externally
• Experience managing cloud infrastructure is required

This position requires someone onsite 5 days per week at our Boston location.

Come to NextRNA as your true self. We value every aspect that makes you unique and want everyone to feel comfortable being who they are while working with us. This is why NextRNA does not discriminate in recruitment, hiring, training, promotion, or other employment practices for reasons of race, color, gender identity or expression, religion, national origin, ancestry, citizenship, physical abilities, neurodiversity, age, sexual orientation, veteran status, or any other legally protected status. We welcome any qualified individual to bring their unique selves to become part of our team.

Please contact NextRNA Head Talent Acquisition for further information
Mary Beth Greene: mgreene@nextrna.com